Special Issue on The Chemical Principles of the Materials Design; Guest Editors: Valery V. Lunin, Stepan N. Kalmykov and Serguei V. SavilovNo Access

Silicon nanoparticles with iron impurities for multifunctional applications

Yu. V. Kargina

http://orcid.org/0000-0001-7477-5579

Lomonosov Moscow State University, Leninskie Gory 1, 119991 Moscow, Russia

National Research Nuclear University MEPhI, Phys-Bio Institute, Kashirskoe Shosse 31, 115409 Moscow, Russia

E-mail Address: [email protected]

Search for more papers by this author

S. V. Zinovyev

National Research Nuclear University MEPhI, Phys-Bio Institute, Kashirskoe Shosse 31, 115409 Moscow, Russia

Blokhin National Medical Research Center of Oncology, Kashirskoe Shosse, 23, 115478 Moscow, Russia

Search for more papers by this author

A. M. Perepukhov

Moscow Institute of Physics and Technology, Dolgoprudny, Institutskij Pereulok, 9, 141701 Moscow Region, Russia

Search for more papers by this author

E. V. Suslova

Lomonosov Moscow State University, Leninskie Gory 1, 119991 Moscow, Russia

Search for more papers by this author

A. A. Ischenko

Russian Technological University MIREA, Lomonosov Institute of Fine Chemical Technologies, Prospekt Vernadskogo, 78, 119454 Moscow, Russia

Search for more papers by this author

, and

V. Yu. Timoshenko

Lomonosov Moscow State University, Leninskie Gory 1, 119991 Moscow, Russia

National Research Nuclear University MEPhI, Phys-Bio Institute, Kashirskoe Shosse 31, 115409 Moscow, Russia

Search for more papers by this author

https://doi.org/10.1142/S179360472040007XCited by:5 (Source: Crossref)

View article

Abstract

Crystalline silicon (Si) nanoparticles (NPs) doped with iron (Fe) in the range from 0.02 to 2.5 at.% were prepared by plasma-ablative synthesis and were investigated by means of the transmission electron microscopy, X-ray diffraction (XRD), dynamic light scattering (DLS), infrared spectroscopy and nuclear magnetic resonance relaxometry. While the nanocrystal size in Si:Fe NPs did not depend significantly on Fe content, the hydrodynamic diameter of NPs in aqueous suspensions increases from 50 to 180nm. Both the transverse and longitudinal proton relaxation time were found to decrease in the prepared suspensions of Si:Fe NPs. Maximal shortening of the transverse relaxion was observed for Si:Fe NPs with 0.2 at.% of Fe and the relaxation rate was almost linearly proportional to the NP concentration. Both these findings and in vivo tests indicate that Si:Fe NPs are promising for biomedical applications in magnetic resonance imaging (MRI) and therapy of cancer.

Keywords:

References

1. L. Mangolini, J. Vac. Sci. Technol. B 31, 020801 (2013). Web of Science, Google Scholar
2. C. M. Gonzalez et al., Nanoscale 6, 2608 (2014). Web of Science, Google Scholar
3. N. O’Farrell et al., Int. J. Nanomed. 1, 451 (2006). Web of Science, Google Scholar
4. Z. Ni et al., Mat. Sci. Eng. R. 138, 85 (2019). Web of Science, Google Scholar
5. Q. S. Luu et al., Appl. Spectrosc. Rev. (2019). https://doi.org/10.1080/05704928.2019.1676255. Google Scholar
6. J. H. Park et al., Nat. Mater. 8, 331 (2009). Web of Science, Google Scholar
7. R. Jugdaohsingh, J. Nutr. Health Aging. 11(2), 99 (2007). Web of Science, Google Scholar
8. E. J. Anglin et al., Adv. Drug. Deliv. Rev. 60(11), 1266 (2008). Web of Science, Google Scholar
9. H. A. Santos et al., Nanomed. 7(9), 1281 (2012). Web of Science, Google Scholar
10. V. Yu. Timoshenko, Porous silicon in photodynamic and photothermal therapy, Handbook of Porous Silicon, ed. L. Canham (Springer, Cham, 2018), pp. 929–936 Google Scholar
11. L. A. Osminkina et al., Micropor.Mesopor. Mat. 210, 169 (2015). Web of Science, Google Scholar
12. A. P. Sviridov et al., Appl. Phys. Lett. 103, 193110 (2013). Web of Science, Google Scholar
13. K. P. Tamarov et al., Sci. Rep. 4, 7034 (2014). Web of Science, Google Scholar
14. V. A. Oleshchenko et al., Appl. Surf. Sci. 516, 145661 (2020). Web of Science, Google Scholar
15. L. Gu et al., Nat. Comm. 4, 2326 (2013). Web of Science, Google Scholar
16. M. Yu. Kirillin et al., Laser Phys. 25, 075604 (2015). Web of Science, Google Scholar
17. A. Yurtsever, Appl. Phys. Lett. 89, 151920 (2006). Web of Science, Google Scholar
18. F. G. Shellock et al., J. Magn. Res. Imag. 10, 477 (1999). Web of Science, Google Scholar
19. H. S. Thomsen et al., Clin. Radiol. 61, 905 (2006). Web of Science, Google Scholar
20. J.-M. Idee et al., Fundam. Clin. Pharmacol. 20, 563 (2006). Web of Science, Google Scholar
21. M. F. Bellin et al., Eur. Radiol. 3(12), 2688 (2003). Web of Science, Google Scholar
22. M. Mahmoudi et al., Chem. Rev. 112, 2323 (2012). Web of Science, Google Scholar
23. B. Godin et al., Acc. Chem. Res. 44(10), 979 (2011). Web of Science, Google Scholar
24. F. Erogbogbo et al., Nanoscale 4(17), 5483 (2012). Web of Science, Google Scholar
25. M. B. Gongalsky et al., Appl. Phys. Lett. 107, 233702 (2015). Web of Science, Google Scholar
26. Yu. V. Kargina et al., J. Appl. Phys. 123, 104302 (2018). Web of Science, Google Scholar
27. Yu. V. Kargina et al., Phys. Stat. Sol. A 216, 1800897 (2019). Google Scholar
28. H. Lim et al., Chem. Commun. 4, 463 (2006). Web of Science, Google Scholar
29. Y. Liu et al., J. Mater. Res. Technol. 8(5), 4470 (2019). Google Scholar
30. A. A. Ischenko, G. V. Fetisov and L. A. Aslanov, Nanosilicon: Properties, Synthesis, Applications, Methods of Analysis and Control (CRC, NY, 2014). Google Scholar
31. B. Aronsson, Acta Chem. Scand. 14, 1414 (1960). Google Scholar
32. D. B. Mawhinney et al., J. Phys. Chem. B 101, 1202 (1997). Web of Science, Google Scholar
33. H. Namduri et al., Corros. Sci. 50, 2493 (2008). Web of Science, Google Scholar
34. L. A. Osminkina et al., Bull. Exp. Biol. Med. 161, 296 (2016). Web of Science, Google Scholar
35. A. F. Alykova et al., J. Phys. Conf. Ser. 945, 010202 (2018). Google Scholar
36. S. J. Dixon et al., Nat. Chem. Biol. 10(7), 9 (2014). Web of Science, Google Scholar