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Special Topic: Research on the Physics of CancerNo Access

From Single-Cell Dynamics to Scaling Laws in Oncology

    https://doi.org/10.1142/S1793048014300035Cited by:3 (Source: Crossref)

    We are developing a biophysical model of tumor biology. We follow a strictly quantitative approach where each step of model development is validated by comparing simulation outputs with experimental data. While this strategy may slow down our advancements, at the same time it provides an invaluable reward: we can trust simulation outputs and use the model to explore territories of cancer biology where current experimental techniques fail. Here, we review our multi-scale biophysical modeling approach and show how a description of cancer at the cellular level has led us to general laws obeyed by both in vitro and in vivo tumors.

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