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Cistanche deserticola Y. C. Ma, "Desert Ginseng": A Review

College of Veterinary Medicine, Northwest A & F University, Yangling, Shaanxi 712100, China

Correspondence to: Dr. Xiaoying Zhang, College of Veterinary Medicine, Northwest A & F University, Post Box No. 19, Xinong Rd. 22, Yangling, Shaanxi 712100, China. Tel/Fax: (+86) 29-8709-1239.

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Wenyan Xie

College of Veterinary Medicine, Northwest A & F University, Yangling, Shaanxi 712100, China

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https://doi.org/10.1142/S0192415X12500838Cited by:74

Abstract

Cistanche deserticola Y. C. Ma (C. deserticola, "Rou Cong Rong" in Chinese) is an officinal plant that grows in arid or semi-arid areas. The dried fleshy stem of C. deserticola has been generally used as a tonic in China and Japan for many years. Modern pharmacology studies have since demonstrated that C. deserticola possesses broad medicinal functions, especially for use in hormone regulation, aperient, immunomodulatory, neuroprotective, antioxidative, anti-apoptotic, anti-nociceptive, anti-inflammatory, anti-fatigue activities and the promotion of bone formation. The phenylethanoid glycosides (PhGs) presented in C. deserticola have been identified as the major active components. This review summarizes the up-to-date and comprehensive information on C. deserticola covering the aspects of the botany, traditional uses, phytochemistry, and pharmacology.

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References

A. S. Ansar, W. J. Penhale and N. Talal, Am. J. Pathol. 121, 531 (1985). Medline, ISI, Google Scholar
E. W. Brenu, L. McNaughton and S. M. Marshall-Gradisnik, Mini Rev. Med. Chem. 11, 438 (2011). Crossref, Medline, ISI, Google Scholar
R. L. Caiet al., Phytother. Res. 24, 313 (2010), DOI: 10.1002/ptr.2927. Crossref, Medline, ISI, Google Scholar
M. H. Chen, F. S. Liu and J. P. Xu, Chin. J. Chin. Mater. Med. 18, 424 (1993). ISI, Google Scholar
China Food and Drug Administration. http://app1.sfda.gov.cn/datasearch/face3/dir.html . Google Scholar
J. G. Choiet al., Behav. Brain Res. 216, 652 (2011), DOI: 10.1016/j.bbr.2010.09.008. Crossref, Medline, ISI, Google Scholar
M. Denget al., Eur. J. Pharmacol. 505, 11 (2004), DOI: 10.1016/j.ejphar.2004.09.059. Crossref, Medline, ISI, Google Scholar
N. S. Du, H. Wang and Y. H. Yi, Nat. Prod. Res. Dev. 5, 5 (1993). Medline, ISI, Google Scholar
Editorial Committee of Chinese Pharmacopoeia. Pharmacopoeia of the People's Republic of China (2005). China Medical Science and Technology Press, Beijing, 2005 . Google Scholar
Editorial Committee of Chinese Pharmacopoeia. Pharmacopoeia of the People's Republic of China (2010). China Medical Science and Technology Press, Beijing, 2010 . Google Scholar
Editorial Committee of Flora Republicae Popularis Sinicae. Flora Republicae Popularis Sinicae. Science Press, Beijing, pp. 86–87 . Google Scholar
R. M. Facinoet al., Planta Med. 61, 510 (1995). Crossref, Medline, ISI, Google Scholar
G. Fu, H. Pang and Y. H. Wong, Curr. Med. Chem. 15, 2592 (2008), DOI: 10.2174/092986708785908996. Crossref, Medline, ISI, Google Scholar
L. G. Fu , China Plant Red Data Book — Rare and Endangered Plants ( Science Press , Beijing , 1992 ) . Google Scholar
X. C. Genget al., Eur. J. Pharmacol. 564, 66 (2007), DOI: 10.1016/j.ejphar.2007.01.084. Crossref, Medline, ISI, Google Scholar
J. Gilet al., Free Radic. Biol. Med. 35, 1500 (2003), DOI: 10.1016/j.freeradbiomed.2003.08.022. Crossref, Medline, ISI, Google Scholar
S. Guanet al., Molecules 16, 3371 (2011), DOI: 10.3390/molecules16043371. Crossref, Medline, ISI, Google Scholar
K. Hayashi, Nat. Med. 58, 307 (2004). Google Scholar
W. Heet al., Chin. J. Chin. Mater. Med. 21, 534 (1996). Google Scholar
W. Heet al., Chin. J. Chin. Mater. Med. 21, 5 (1996). Google Scholar
Z. D. Heet al., J. Nat. Prod. 66, 851 (2003), DOI: 10.1021/np020568g. Crossref, Medline, ISI, Google Scholar
L. C. Hofbauer and S. Khosla, Eur. J. Endocrinol. 140, 271 (1999), DOI: 10.1530/eje.0.1400271. Crossref, Medline, ISI, Google Scholar
Y. M. Jiaet al., J. Pharmacol. Sci. 118, 99 (2011), DOI: 10.1254/jphs.11186FP. Crossref, Medline, ISI, Google Scholar
Y. Jiang and P. F. Tu, J. Chromatogr. A 1216, 1970 (2009). Crossref, Medline, ISI, Google Scholar
K. A. Kooet al., Planta Med. 71, 778 (2005), DOI: 10.1055/s-2005-871213. Crossref, Medline, ISI, Google Scholar
B. R. Li and Y. C. She, J. Tradit. Chin. Med. 7, 63 (1984). Medline, ISI, Google Scholar
G. Liet al., Lishizhen Med. Mater. Med. Res. 21, 2205 (2010). Google Scholar
J. Liet al., Planta Med. 59, 315 (1993). Medline, ISI, Google Scholar
T. Liet al., Phytomedicine 14, 601 (2007), DOI: 10.1016/j.phymed.2006.12.016. Crossref, Medline, ISI, Google Scholar
T. M. Liet al., J. Pharm. Pharmacol. 64, 897 (2012), DOI: 10.1111/j.2042-7158.2012.01483.x. Crossref, Medline, ISI, Google Scholar
W. L. Liet al., J. Ethnopharmacol. 83, 177 (2002). Medline, ISI, Google Scholar
W. J. Li, X. H. Teng and Z. C. Wu, J. Shanghai Rail. Med. Coll. 9, 179 (1995). Google Scholar
W. N. Linet al., Am. J. Chin. Med. 38, 205 (2010), DOI: 10.1142/S0192415X10007762. Link, ISI, Google Scholar
X. M. Liuet al., Chin. Pharm. J. 46, 1053 (2011). Google Scholar
K. G. Lu, H. B. Liu and Q. Q. Gu, Food Drug 11, 18 (2009). Google Scholar
S. S. Luo, Y. Gu and Y. H. Liu, Bull. Chin. Mater. Med. 11, 41 (1986). ISI, Google Scholar
H. Y. Luoet al., Chin. J. Clin. Pharmacol. Ther. 14, 1225 (2009). Google Scholar
H. Y. Luo, H. Liu and H. Yang, Chin. J. Clin. Pharmacol. Ther. 16, 856 (2011). Google Scholar
T. Morikawaet al., Bioorgan. Med. Chem. 18, 1882 (2010), DOI: 10.1016/j.bmc.2010.01.047. Crossref, Medline, ISI, Google Scholar
J. Panet al., Pharmazie 58, 767 (2003). Medline, ISI, Google Scholar
L. Penget al., Appl. Prev. Med. 17, 47 (2011). ISI, Google Scholar
X. P. Puet al., Planta Med. 69, 65 (2003), DOI: 10.1055/s-2003-37029. Crossref, Medline, ISI, Google Scholar
G. Q. Shenget al., Planta Med. 68, 966 (2002), DOI: 10.1055/s-2002-35667. Crossref, Medline, ISI, Google Scholar
T. Y. Shiet al., Neurotox. Res. 21, 358 (2012), DOI: 10.1007/s12640-011-9290-7. Crossref, Medline, ISI, Google Scholar
Y. M. Shiet al., Mutagenesis 1, 19 (2008). ISI, Google Scholar
S. H. Sunget al., Planta Med. 72, 62 (2006), DOI: 10.1055/s-2005-873140. Crossref, Medline, ISI, Google Scholar
D. Y. Tan, Q. S. Guo and C. L. Wang, Forest Resour. Manage. 2, 29 (2004). Google Scholar
The Endangered Species Import and Export Management Office of the People's Republic of China, Endangered Species Scientific Commission, P. R. C. Convention on international trade in endangered species (CITES): Appendix II. 2003 . Google Scholar
P. F. Tuet al., Acta Pharm. Sin. 32, 294 (1997). Google Scholar
P. F. Tuet al., Chin. Pharm. J. 46, 882 (2011). Google Scholar
G. W. Wang and F. Zhao, Chin. J. Spect. Lab. 28, 1545 (2011). Google Scholar
H. Wanget al., J. Chin. Integr. Med. 5, 407 (2007), DOI: 10.3736/jcim20070409. Crossref, ISI, Google Scholar
X. Y. Wanget al., Acta Lab. Anim. Sci. Sin. 17, 424 (2009). ISI, Google Scholar
X. Y. Wanget al., Chin. Pharm. Bull. 25, 787 (2009). Google Scholar
Y. L. Wuet al., Biol. Pharm. Bull. 31, 1523 (2008), DOI: 10.1248/bpb.31.1523. Crossref, Medline, ISI, Google Scholar
J. N. Xieet al., Chin. Tradit. Herb. Drugs 2, 268 (2005). Google Scholar
Q. Xionget al., Biol. Pharm. Bull. 19, 1580 (1996), DOI: 10.1248/bpb.19.1580. Crossref, Medline, ISI, Google Scholar
Q. Xionget al., Planta Med. 64, 120 (1998), DOI: 10.1055/s-2006-957387. Crossref, Medline, ISI, Google Scholar
Q. Xionget al., Eur. J. Pharmacol. 400, 137 (2000), DOI: 10.1016/S0014-2999(00)00354-X. Crossref, Medline, ISI, Google Scholar
R. Xuet al., Genet. Resour. Crop. Evol. 56, 137 (2009), DOI: 10.1007/s10722-008-9383-1. Crossref, ISI, Google Scholar
W. H. Xuet al., Chin. Tradit. Herb. Drugs 25, 509 (1994). Google Scholar
Z. H. Xu, J. S. Yang and R. M. Lv, Chin. Tradit. Herb. Drugs 30, 244 (1999). Google Scholar
G. D. Xuan and C. Q. Liu, J. Chin. Med. Mater. 31, 1385 (2008). Google Scholar
P. Yamadaet al., Planta Med. 76, 1512 (2010), DOI: 10.1055/s-0030-1249775. Crossref, Medline, ISI, Google Scholar
H. J. Yanet al., Am. J. Chin. Med. 38, 473 (2010), DOI: 10.1142/S0192415X10007993. Link, ISI, Google Scholar
J. H. Yanget al., J. Chin. Med. Mater. 32, 1067 (2009). Google Scholar
M. Yoshikawaet al., Bioorgan. Med. Chem. 14, 7468 (2006), DOI: 10.1016/j.bmc.2006.07.018. Crossref, Medline, ISI, Google Scholar
J. C. Zenget al., China J. Orthop. Trauma 23, 606 (2010). Google Scholar
Q. L. Zeng, J. H. Mao and Z. L. Lv, J. Zhejiang Univ. Sci. 7, 108 (1998). Google Scholar
Q. L. Zeng, Y. F. Zheng and Z. L. Lu, J. Zhejiang Univ. Sci. 31, 284 (2002). Google Scholar
B. S. Zhang, J. Chin. Med. Mater. 15, 33 (1992). ISI, Google Scholar
T. Zhanget al., Sci. Tech. Food Ind. 30, 155 (2009). ISI, Google Scholar

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Cistanche deserticola Y. C. Ma, "Desert Ginseng": A Review

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