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    The Maximum Isomorphic Agreement Subtree problem is one of the simplest versions of the Maximum Interval Weight Agreement Subtree method which is used to compare phylogenies. More precisely allows to provide a subset of the species such that the exact distances between species in such subset are preserved among all evolutionary trees considered. In this paper, the approximation complexity of the MIT problem is investigated, showing that it cannot be approximated in polynomial time within factor logδn for any δ > 0 unless NPDTIME(2polylog n) for instances containing three trees. Moreover, we show that such result can be strengthened whenever instances of the problem can contain an arbitrary number of trees, since shares the same approximation lower bound of .

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